Journal of the Chemical Society. Perkin transactions I p. 1007 - 1011 (1989)
Update date:2022-08-03
Topics:
Nuvole, Antonio
Paglietti, Giuseppe
An investigation of the additions of (E)-enamino amides (1a-d) with DMAD has shown that they are influenced by the stereochemistry of the intermediates and the amine component of the enamine system.In dry acetonitrile (E)- benzyl(methyl)amino- (1b), (E)-pyrrolidin-1-ylamino-(1c), and (E)-piperidin-1-ylamino-(1d) acrylamides, following a known mechanism, yielded tetramethyl benzene-1,2,3,4-tetracarboxylate (5), the (E)-aminobutenedioates (6a-d), and the 3,4-bismethoxycarbonylpyridin-2(1H)-one (8).Dimethylamino-(1a) and morpholin-1-ylamino-(1e)-acrylamides, owing to the different nucleophilicity of the β-carbon, formed a zwitterion (11) which eliminated propiolamide to give only the (E)-aminobutenedioates (6a,e).
View Morewebsite:http://www.amadischem.com
Contact:86-571-89925085
Address:Watts Cosine.No.166.Xiangmao Road.
Shanghai Korey Pharm Co.,Ltd.(expird)
Contact:021-61840961 021-61840962
Address:No.157,Zhuguang Rd, Qingpu, Shanghai, China
Anhui Gusheng Import&Export CO.,LTD
Contact:86-551-63662296
Address:Jinzhai Road NO.162 ,hefei, china
Hunan Dinuo Pharmaceutical Co.,Ltd.
Contact:86-731-88280100*8561
Address:Bio-pharmaceutical industrial park, Liuyang, Hunan, China
Tianjin Jingye Fine Chemicals Co., Ltd.
Contact:+86-15722078107; +86-22-26911407
Address:Bohua Fine Chemicals Base of Petrochemical Industry Park, Nanhuan Road, Dagang District, Tianjin, 300271, P. R. China
Doi:10.1021/jo048233m
(2005)Doi:10.1016/j.bmcl.2004.12.039
(2005)Doi:10.1002/hc.20061
(2005)Doi:10.1002/adsc.200404089
(2004)Doi:10.1007/s11178-005-0057-6
(2004)Doi:10.1039/P19840000839
(1984)
