SYNTHESE DES 2-AMINO-2-DESOXY-D-ARABINONO- ET -D-XYLONO-LACTONES PAR CONDENSATION D'ACIDES AMINES AVEC LE D-GLYCERALDEHYDE. ANALYSE STRUCTURALE PAR RAYONS X DE DEUX DERIVES

Article abstract of DOI:10.1016/0008-6215(83)88265-2

Synthesis of 2-amino-2-deoxy-D-pentonolactones was performed by diastereoselective hydroxyalkylation of 2,3-O-isopropylidene-D-glyceraldehyde with ethyl isocyanoacetate, to give two oxazolines in a ratio of 7:3.Hydrolysis gave first the corresponding amid