A new synthesis of alkyl-1-alkyl-2-methylpyrrole-3-carboxylates by ring transformation of 2-chloro-2-acetimidoylbutyrolactones

DOI: 10.1016/S0040-4020(99)00108-8

Source and publish data:

Tetrahedron p. 4153 - 4166 (1999)

Update date:2022-08-03

Topics:

Authors:

Kesteleyn, Bart

Alonso, Erick Rosas

Stevens, Christian

Dejaegher, Yves

Peristeropoulou, Maria

Nguyen Van, Tuyen

Kulinkovich, Oleg

De Kimpe, Norbert

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Article abstract of DOI:10.1016/S0040-4020(99)00108-8

Reaction of 2-chloro-2-acetimidoylbutyrolactones with sodium methoxide or sodium ethoxide in the corresponding alcohol provides a facile one-step synthesis of methyl or ethyl 1-alkyl-2-methylpyrrole-3-carboxylates from readily available starting materials.

Full text of DOI:10.1016/S0040-4020(99)00108-8

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