Bioorganic and Medicinal Chemistry Letters p. 1055 - 1059 (2005)
Update date:2022-08-04
Topics:
Ochi, Takeshi
Sakamoto, Masato
Minamida, Akira
Suzuki, Kenji
Ueda, Tomohiko
Une, Teruaki
Toda, Hiroshi
Matsumoto, Kazuya
Terauchi, Yoshiaki
Two major metabolites in humans of blonanserin, 2-(4-ethyl-1-piperazinyl)- 4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta-[b]pyridine (code name AD-5423), were synthesized. The first, 7-hydroxylated AD-5423, was synthesized through a four-step process
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(2005)Doi:10.1016/j.bmc.2004.12.041
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