Synthetic studies on halichondrins: A new practical synthesis of the C.1-C.12 segment

DOI: 10.1016/S0040-4039(00)60394-5

Source and publish data:

Tetrahedron Letters p. 7541 - 7544 (1993)

Update date:2022-07-31

Topics:

Authors:

Duan Duan

Kishi Kishi

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Article abstract of DOI:10.1016/S0040-4039(00)60394-5

A new practical synthesis of the C.1-C.12 halichondrin segment was achieved from L-mannonic γ-lactone (5), using osmylation, C-allylation and Michael reaction as key steps.

Full text of DOI:10.1016/S0040-4039(00)60394-5

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Product name:2,3:5,6-DI-O-ISOPROPYLIDENE-L-MANNOFURANOSE

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