Chiral zirconium catalysts using multidentate BINOL derivatives for catalytic enantioselective Mannich-type reactions; ligand optimization and approaches to elucidation of the catalyst structure

Article abstract of DOI:10.1021/ja053524d

Catalytic enantioselective Mannich-type reactions of silicon enolates with aldimines were investigated using chiral zirconium catalysts prepared from Zr(O^tBu)₄, N-methylimidazole, and newly designed multidentate BINOL derivatives. Th