Highly Efficient Asymmetric Reduction of α-Tertiary Alkyl Ketones with Diisopinocampheylchloroborane

Article abstract of DOI:10.1021/jo00367a037

(-)-Diisopinocampheylchloroborane, which reduces many aralkyl and heteroaralkyl ketones with remarkably high stereoselectivity, has now been found to reduce α-tertiary alkyl ketones with similar high enantiomeric excess.Such ketones have resisted asymmetr