Novel synthetic (1 → 6)-α-d-mannodisaccharide substrates support processive mannosylation catalysed by the mycobacterial cell envelope enzyme fraction

Article abstract of DOI:10.1039/c3ra43575j

Three new (1 → 6)-α-d-mannodisaccharides with cyclohexylalkyl or octylsulfonyl function like aglycone were synthesized and screened in the mycobacterial mannosyltransferase assay. 2-Cyclohexylethyl (1 → 6)-α-d-Man2 acted as the best acceptor substrate, wh