Preparation of iodine-123 labeled AM251: A potential spect radioligand for the brain cannabinoid CB1 receptor

DOI: 10.1002/(SICI)1099-1344(199610)38:10<875::AID-JLCR908>3.0.CO;2-G

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 875 - 881 (1996)

Update date:2022-08-03

Topics:

Authors:

Lan, Ruoxi

Gatley, S. John

Makriyannis, Alexandros

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/(SICI)1099-1344(199610)38:10<875::AID-JLCR908>3.0.CO;2-G

We report the synthesis and labeling with iodine-123 of N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole -3-carboxamide (AM251). This compound is an anlog of the recently described cannabinoid receptor antagonist, R141716A,

Full text of DOI:10.1002/(SICI)1099-1344(199610)38:10<875::AID-JLCR908>3.0.CO;2-G

Products guided by the article

Product name:Lithium, [1-(4-bromobenzoyl)-3-ethoxy-1-methyl-2,3-dioxopropyl]-

Cas No:850554-39-1

R&D Labs maybe for 850554-39-1

Suzhou JMS Chemical Co., Ltd.

Contact:+86-15995924277

Address:WuZhongOu suzhou new south road 89
CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd

Contact:+86-0517-87036900

Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Water Chemical Co.,LTD

Contact:+86-21-6856-1349 523-87676172

Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
Qingdao Pharmacypro Co., Ltd.

Contact:+86-532-55689660

Address:qingdao

Relevant to this article

Novel trifluoromethyl sydnone derivatives: Design, synthesis and fungicidal activity

Doi:10.1016/j.bmcl.2021.128114
(2021)
Reactions with heterocyclic enamines. Synthesis of new isoxazole derivatives

Doi:10.1002/ardp.19833160204
(1983)
Isoindolo[2,1-c][2,3]benzodiazepines

Doi:10.1002/ardp.19833160205
(1983)
First enantiospecific synthesis of (+)-β-herbertenol

Doi:10.1016/j.tet.2005.01.050
(2005)
Synthesis of monomers bearing at the 2′-position cyanomethoxycarbonyl group for phosphoramidite oligonucleotide synthesis

Doi:10.1081/NCN-200026053
(2004)
In vitro characterization of salmochelin and enterobactin trilactone hydrolases IroD, IroE, and Fes

Doi:10.1021/ja0522027
(2005)

Article Doi