Antihypertensive 9-substituted 1-oxa-4,9-diazaspiro[5.5]undecan-3-ones

DOI: 10.1021/jm00360a013

Source and publish data:

Journal of Medicinal Chemistry p. 855 - 861 (1983)

Update date:2022-08-04

Topics:

Authors:

Clark Clark

Caroon Caroon

Repke Repke

Strosberg

Bitter Bitter

Okada Okada

Michel Michel

Whiting Whiting

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00360a013

Forty-one 9-substituted 1-oxa-4,9-diazaspiro[5.5]undecan-3-ones were prepared for antihypertensive screening in the spontaneously hypertensive rat (SHR). For the 9-(2-indol-3-ylethyl) series, the parent compound 9-(2-indol-3-ylethyl)-1-oxa-4,9-diazaspiro[

Full text of DOI:10.1021/jm00360a013

Products guided by the article

Product name:1-Oxa-4,9-diazaspiro[5.5]undecan-3-one, 4-phenyl-

Cas No:85151-19-5

R&D Labs maybe for 85151-19-5

Wuxi Pharma-Trading Import & Export Co.,Ltd.

Contact:+86-510-82304590 82716390

Address:Room 523,Youzu Alliance Building,No.88 Renmin Zhonglu,Wuxi,Jiangsu,China
Synchemie Co., Ltd.

website:http://www.synchemie.com/

Contact:+86-574-87642758

Address:Room 901, Yinyi Bund Building， 132 Renmin Road
Skyrun Industrial Co.,Ltd(expird)

website:http://www.chinaskyrun.com

Contact:0086-576-84610586

Address:Chemical Development Zone
Angelisun(Chongqing) Pharmaceutical Co., LTD.

Contact:+86-23-68030926-816

Address:D1-7 Tech & Entrepreneurs Park, Kecheng Road, Erlang Hi-Tech Areas, Chongqing, China
Aminodiscovery Co.,Ltd.

Contact:+86-535-8888888

Address:No.161 Haishi Rd.

Relevant to this article

Palladium(I) ? Radicals. Electrochemical Preparation and Study of Their Reaction Pathways

Doi:10.1021/ja00236a018
(1987)
Three-spin system with a twist: A bis(semiquinonato)copper complex with a nonplanar configuration at the copper(II) center

Doi:10.1002/anie.200462339
(2005)
Pendant arm functionalized benzamidinate titanium imido compounds: Experimental and computational studies of their reactions with CO₂

Doi:10.1021/om049026f
(2005)
Interaction of α-Thymidine Inhibitors with Thymidylate Kinase from Plasmodium falciparum

Doi:10.1021/acs.biochem.8b00162
(2018)
C-C coupling of aryl groups and allyl derivatives on Pt(II)-phenanthroline fragments: Crystal and molecular structure of the tbp [(η¹, η²-2-allyl,5-methyl-phenyl)iodo(1,10-phenanthroline)platinum(II)] complex containing the N-N ligand in axial-equatorial coordination mode

Doi:10.1016/j.jorganchem.2004.12.010
(2005)
Synthesis of fused bicyclic pyridines with microwave-assisted intramolecular hetero-Diels-Alder cycloaddition of acetylenic pyrimidines

Doi:10.1016/j.tetlet.2005.03.098
(2005)

Article Doi