
Tetrahedron Letters p. 5041 - 5044 (1997)
Update date:2022-08-04
Topics:
Capozzi, Giuseppe
Corti, Alessandra
Menichetti, Stefano
Nativi, Cristina
α-Oxothioaldehyde S-oxides 4a-f can be generated under very mild conditions from the corresponding sulfinyl compounds 3a-f, which in turn are obtained by m-chloroperoxybenzoic acid (MCPBA) oxidation of α- oxothiophthalimides 2a-f. The reactive sulfine intermediates can be trapped as electron-poor dienophiles as well as electron-poor dienes with formation of dihydrothiopyran S-oxides 5a-e or 1,4-oxathiin S-oxides 6a-f, respectively.
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