Tetrahedron p. 2725 - 2727 (1982)
Update date:2022-07-29
Topics:
Colombo, L.
Gennari, C.
Poli, G.
Scolastico, C.
The synthesis of two S-proline derivatives is described together with their use as chiral ligands for lithium in reactions of n-butyllithium with benzaldehyde to give 1-phenyl-1-pentanol with moderate optical purity.The presence of lithium salts in the reaction mixture causes a decrease in asymmetric induction.
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