Convergent synthesis of (-)-mirabazole B using a chloroimidazolidium coupling reagent, CIP

Article abstract of DOI:10.1016/S0040-4020(97)00523-1

(-)-Mirabazole B (1), an alkaloid consisting of four successive thiazoline/thiazole rings, has been synthesized in a convergent route. The key intermediate, a linear tripeptide amide 13 composing of three S-benzyl-2-methylcysteine residues, was prepared u