Analgesic narcotic antagonists. XV. Potent narcotic agonist 7β-(arylalkyl)-4,5α-epoxymorphinans

DOI: 10.1021/jm00361a019

Source and publish data:

Journal of Medicinal Chemistry p. 1050 - 1056 (1983)

Update date:2022-09-26

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Authors:

Kotick Kotick

Leland Leland

Polazzi Polazzi

Howes Howes

Bousquet

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Article abstract of DOI:10.1021/jm00361a019

Structure-activity correlations in 7β-(arylalkyl)-3-methoxy- or -hydroxy-4,5α-epoxymorphinans have been investigated. 6β-Hydroxy-7α-hydroxymethyl compounds 7 with 7β-substituents CH₂CH₂R [a, R = H; b, R = CH₂CH₃

Full text of DOI:10.1021/jm00361a019

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