Steric and Electronic Effects in SN2 reactions of 9-Substituted Fluorenyl and α-Cyano Carbanions with Benzyl Chloride in Dimethyl Sulfoxide Solution

Article abstract of DOI:10.1021/jo00161a015

Rates of reactions of PhCH2Cl with carbanions derived from six α-cyano carbon acids of varied structure with pK_a values ranging over 16 units have been measured.When placed on a log k vs. pK_a plot the points fit near to the extended