Journal of Organic Chemistry p. 2226 - 2233 (1983)
Update date:2022-09-26
Topics:
Ford, George P.
Scribner, John D.
A simple method is presented for predicting the hydration free energies of certain organic cations on the basis of additive group contributions and an electrostatic component.Approximate hydration effects accompanying protonation or alkylation of various functional groups are tabulated and illustrated with reference to published data on benzylation of adenosine and guanosine in aqueous mixtures.
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