Journal of medicinal chemistry p. 1461 - 1468 (1986)
Update date:2022-07-30
Topics:
Johnson
Nidy
Aiken
Crittenden
Gorman
The synthesis and screening of a series of 5-(3-pyridylmethyl)benzofuran-2-carboxylic acids as selective thromboxane A2 (TxA2) synthase inhibitors is outlined. The ability of these compounds to inhibit TxA2 biosynthesis was assayed using microsomal enzyme
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