Thromboxane A2 synthase inhibitors. 5-(3-Pyridylmethyl)benzofuran-2-carboxylic acids.

DOI: 10.1021/jm00158a024

Source and publish data:

Journal of medicinal chemistry p. 1461 - 1468 (1986)

Update date:2022-07-30

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Authors:

Johnson Johnson

Nidy Nidy

Aiken Aiken

Crittenden

Gorman Gorman

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Article abstract of DOI:10.1021/jm00158a024

The synthesis and screening of a series of 5-(3-pyridylmethyl)benzofuran-2-carboxylic acids as selective thromboxane A2 (TxA2) synthase inhibitors is outlined. The ability of these compounds to inhibit TxA2 biosynthesis was assayed using microsomal enzyme

Full text of DOI:10.1021/jm00158a024

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