Studies on analgesic oligopeptides. II. Structure-activity relationship among thirty analogs of a cyclic dipeptide, cyclo(-Tyr-Arg-)

DOI: 10.1248/cpb.30.4435

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 4435 - 4443 (1982)

Update date:2022-07-30

Topics:

Authors:

Sasaki Sasaki

Akutsu Akutsu

Matsui Matsui

Suzuki Suzuki

Sakurada

Sato Sato

Kisara Kisara

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.30.4435

Thirty diketopiperazines were synthesized as analogs of cyclo(-Tyr-Arg-). The analgesic activities of these analogs were evaluated after intracerebral administration in mice. In the cyclo(-X-Arg-) series of analogs, cyclo[-Tyr(Et)-Arg-] showed the most po

Full text of DOI:10.1248/cpb.30.4435

NII-Electronic Library Service

Products guided by the article

Product name:Boc-Dab(Z)-Tyr-OBzl

Cas No:85676-36-4

R&D Labs maybe for 85676-36-4

Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China
Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China
MINS GROUP CO.,LIMITED

Contact:18669908765

Address:Zibo City, Shandong Province, P.R.China
N&R INDUSTRIES,INC

Contact:Tel:+86-29-88764861 Fax:+86-29-88764861

Address:Rm#2107, Block A, Epin Meidao Building, Gaoxin Rd, Hi-Tech Zone, Xi’an, China
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park

Relevant to this article

Doi:10.1002/hlca.19500330535
(1950)
Doi:10.1021/ja01100a032
(1953)
HOMOLOGATION OF N-ALKANES USING DIAZOESTERS AND RHODIUM(III)PORPHYRINS. ENHANCED ATTACK ON PRIMARY C-H BONDS.

Doi:10.1016/S0040-4039(00)85590-2
(1982)
Chemoenzymatic synthesis of D-N-Boc-3,5-dihydroxy-4- methoxyphenylglycine

Doi:10.1021/jo980233x
(1998)
Doi:10.1039/jr9400000874
(1940)
TWO-DIMENSIONAL DYNAMICAL JAHN-TELLER EFFECTS IN A MIXED-VALENCE BENZOTRIAZOLATO COPPER CLUSTER, Cu₅(BTA)₆(RNC)₄.

Doi:10.1021/ja00355a017
(1983)

Article Doi