Bioorganic and Medicinal Chemistry Letters p. 2607 - 2612 (1996)
Update date:2022-07-30
Topics:
Di Stilo
Cena
Gasco
Gasco
Ghigo
Bosia
The cellular mechanism of bioactivation underlying guanylate cyclase activation by the pair of phenylfuroxancarbonitrile isomers 2a, b was investigated. In cultured rat lung fibroblast (RFL-6 cells) it was principally dependent on intracellular thiols.
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