Configurationally selective transition state analogue inhibitors of glycosidases. A study with nojiritetrazoles, a new class of glycosidase inhibitors

Article abstract of DOI:10.1016/0008-6215(93)84160-8

"Mannonojiritetrazole" (7), a novel mannosidase inhibitor, has been synthesized in six steps from 2,3,4,6-tetra-O-benzyl-D-mannose oxime.The structure of 7 has been established by X-ray analysis.The solid state conformation of 7 is ⁶H₇