Bioorganic and Medicinal Chemistry Letters p. 4421 - 4426 (2005)
Update date:2022-08-03
Topics:
Caijo, Frederic
Mosset, Paul
Gree, Rene
Audinot-Bouchez, Valerie
Boutin, Jean
Renard, Pierre
Caignard, Daniel-Henri
Dacquet, Catherine
A new class of dual PPARs α and γ agonists was developed. These compounds are structural analogues of the arachidonic acid metabolite, the 8-(S)-HETE. A versatile strategy has been introduced to prepare the target molecules having different carbo- and het
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