Organic Letters
Letter
(12) Alachouzos, G.; Frontier, A. J. J. Am. Chem. Soc. 2019, 141,
118−122.
(13) It was discovered that 1 equiv of Tf2NH worked best for
assorted enyne and arenyne cases, ensuring the full consumption of
N,O-acetal (cf. 11).
ACKNOWLEDGMENTS
■
We are grateful to the National Science Foundation (CHE-
1900050) and the Petroleum Research Fund (58776-NDI) for
the funding of this project.
(14) The conformational equilibria of seven-membered carbocycles
are well known: (a) Hendrickson, J. B. J. Am. Chem. Soc. 1967, 89,
7047−7061. (b) Katritzky, A. R.; Akhmedov, N. G.; Ghiviriga, I.;
Maimait, R. N. G. J. Chem. Soc., Perkin Trans. 2 2002, 1986−1993.
(15) Electron-deficient arenynes tested: p-NO2, 2-pyridyl, p-bromo,
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