Tetraformyltetrathiafulvalene (TFTTF) and acetals, precursors of polyfunctionalized TTFs

Article abstract of DOI:10.1016/S0040-4020(01)92250-1

A short synthesis of 1,3-dithiol-2-thiones bearing two aldehyde functionalities, free and/or masked as diethylacetals is described. They are shown to be convenient precursors for synthesizing di- and tetraformyl-TTF. When submitted to four-fold nucleophilic attacks, the latter readily affords new substituted derivatives such as the bis-(pyridazino)-TTF 8, the tetrakis-(hydroxymethyl)-TTF 9 and the tetravinylic-TTF 10 whose π-donor ability has been characterized.