Inverse Electron Demand Diels-Alder Reactions of 4,6-Dimethyl-2-oxo-2H-pyran-5-carboxylic Acid Esters and Morpholino Enamines: Regiospecific Preparation of 3- or 4-Substituted-2,6-dimethylbenzoates

DOI: 10.1021/jo00173a017

Source and publish data:

Journal of Organic Chemistry p. 4869 - 4873 (1983)

Update date:2022-08-03

Topics:

Authors:

Gingrich, Henry L.

Roush, David M.

Saun, William A. Van

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00173a017

Previously, α-pyrones have been used as dienes in cycloaddition reactions with enamines to form adducts that, upon eliminationof carbon dioxide via a cycloreversion reaction and concomitant aromatization through amine elimination, provided sustituted aryl

Full text of DOI:10.1021/jo00173a017

Products guided by the article

Product name:1,5-Cyclohexadiene-1-carboxylic acid, 2,3,6-trimethyl-4-(4-morpholinyl)-, ethyl ester, trans-

Cas No:87555-76-8

R&D Labs maybe for 87555-76-8

Xinchang Yueding Chemical Co., Ltd.

Contact:86-571-56926323

Address:NO.90 BEIMENCHENGWAI CHENGGUAN TOWN XINCHANG
Shanghai Rainbow Chemistry Co., Ltd.

Contact:+86-21-64968086-5815/5812

Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing
Chiral Quest (Suzhou) Company Ltd

website:http://www.chiralquest.com

Contact:+86-0512-62956066

Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China

Relevant to this article

Design, synthesis, and structure-activity relationships of 3,4,5-trisubstituted 4,5-dihydro-1,2,4-oxadiazoles as TGR5 agonists

Doi:10.1002/cmdc.201300144
(2013)
A Fresh Look at the Staudinger Reaction on Azido Esters: Formation of 2H-1,2,3-Triazol-4-ols from α-Azido Esters Using Trialkyl Phosphines

Doi:10.1021/acs.orglett.6b02204
(2016)
Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

Doi:10.1016/j.bmcl.2010.04.079
(2010)
Rhodium-catalyzed asymmetric conjugate additions of boronic acids to enones using DIPHONANE: A novel chiral bisphosphine ligand

Doi:10.1021/ol0522788
(2006)
A Direct Synthesis of β-Hydroxybutyrolactones: Total Synthesis of Dendrolasin and Formal Total Synthesis of Aplysistatin

Doi:10.1021/jo00174a038
(1983)
α-Alkoxyallylation of Activated Carbonyl Compounds. A Novel Variant of the Michael Reaction

Doi:10.1021/jo00175a030
(1984)

Article Doi