A NEW METHOD FOR THE PREPARATION OF N-(NUCLEOSIDYL)-α-AMINO ACIDS USING TRIOCTYLMETHYLAMMONIUM SALTS OF α-AMINO ACIDS

Article abstract of DOI:10.1016/S0040-4039(00)88170-8

8-Bromoadenosine reacts with trioctylmethylammonium salts of α-amino acids (e.g. glycine) to yield N-(adenosin-8-yl)-α-amino acids which can be readily separated from the starting material by two subsequent extraction steps at different pH values.