Carbohydrate Research p. 21 - 30 (1983)
Update date:2022-08-04
Topics:
Rasmussen, James R.
Tafuri, Sherrie R.
Smale, Stephen T.
Addition of potassium cyanide to 2-deoxy-2-fluoro-D-arabinose (1) at pH 7.8 followed by catalytic hydrogenation over palladium-barium sulfate (5percent) produced 3-deoxy-3-fluoro-D-glucose (4) and 3-deoxy-3-fluoro-D-mannose (5) in 25 and 40 percent isolated yields, respectively.The epimeric sugars were purified by passage through a column of Dowex-50W x 8 (Ca2+).In a similar manner, 3-deoxy-3-fluoro-D-arabinose (6) was converted into 4-deoxy-4-fluoro-D-glucose (9) and 4-deoxy-4-fluoro-D-mannose (10) in 27 and 45 percent isolated yields, respectively.Deoxyfluorohexoses 4,5,9 and 10 enriched with carbon-13 and crbon-14 at C-1 have been prepared by this procedure.
View MoreContact:86-25-84683399
Address:605, Phoenix Herui Plaza, No.389, South Taiping Road, Nanjing, China 210002
Arshine Pharmaceutical Co., Limited
website:http://www.cnarshine.com
Contact:0731-88503671
Address:Room 1109.Block C3, Lugu Enterprise Plaza,No.27 Wenxuan Road,Changsha National Hi-Tech Industrial Development Zone,Hunan ,P.R.China
Contact:+86-518-81061113
Address:No. 8 Lingzhou Road, Lianyungang, Jiangsu, China
website:http://www.orchid-chem.com
Contact:+86-571-85395792
Address:607, North Zhongshan Road, Hangzhou 310000 China
Yueyang Hudex Pharmaceuticals Ltd.
Contact:0730-8748800
Address:Wujiang Bridge，Yueyang Economy & Technology Development Zone
Doi:10.1248/cpb.42.802
(1994)Doi:10.1021/ic051487l
(2006)Doi:10.1016/j.ejmech.2013.10.030
(2013)Doi:10.1002/ejic.201100119
(2011)Doi:10.1021/jf048994q
(2005)Doi:10.1016/j.bmc.2009.01.023
(2009)
