Tetrahedron Letters p. 5483 - 5486 (1999)
Update date:2022-08-05
Topics:
Mongin, Florence
Trecourt, Francois
Queguiner, Guy
The lithium salts of 2-, 3- and 4-pyridinecarboxylic acids undergo deprotonation at the position adjacent to the carboxylate group when treated with LTMP in THF at 0 °C, -50 °C and -25 °C, respectively. The lithiation conditions could be extended to chlor
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