Journal of the Chemical Society. Perkin transactions I p. 2563 - 2567 (1983)
Update date:2022-08-04
Topics:
Kirk, David N.
Varley, Michael J.
Makin, Hugh L.J.
Trafford, David J.H.
The carbanion derived from 24-phenylsulphonylchol-5-en-3β-ol 3-tetrahydropyranyl ether (6) reacted with <2H6>acetone to give the 24-phenylsulphonyl-25-hydroxy<26,27-2H6>cholesterol derivative (7a), which was reduced by sodium amalgam to a separable mixture of the labelled 25-hydroxycholesterol and cholest-5,24-dien-3β-ol (desmosterol) derivatives. <26,27-2H6>Cholesterol has been obtained via a selective reduction of the Δ24-unsaturation in <26,27-2H6>desmosteryl benzoate with di-imide, or more efficiently by reducing 25-hydroxy<26,27-2H6>cholesteryl 3,25-diacetate w ith litium in ethylamine, without significant loss of label.The labelled 24,25-dihydroxycholesterols were also prepared from <26,27-2H6>desmosteryl benzoate.
View MoreYantai Derun Liquid Crystal Materials Co. Ltd.
website:http://www.ytderun.com
Contact:86-535-6300169
Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
Chemieliva Pharmaceutical Co., Ltd.
website:http://www.chemieliva.com
Contact:+86-23-67770219
Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang
Contact:+86-0311-84455288-844
Address:Mayu Industrial Park, Jinzhou, Hebei, China.
Nanjing distinctions Medical Technology Co., Ltd.(expird)
Contact:+86-15996203785 13914714059
Address:nanjing,jiangsu , China
Hangzhou Bayee Chemical Co.,Ltd.
Contact:+86-571-86990109
Address:No.380, Jiangnan Auenue, Binjiang District, Hangzhou, China
Doi:10.1016/S0040-4039(00)85948-1
(1983)Doi:10.1021/ja01630a045
(1954)Doi:10.1007/BF00505751
(1983)Doi:10.1016/S0040-4020(01)91186-X
(1984)Doi:10.1016/j.tetlet.2006.01.135
(2006)Doi:10.1021/ol060106k
(2006)
