Synthesis and evaluation of novel macrocyclic and acyclic ligands as contrast enhancement agents for magnetic resonance imaging

DOI: 10.1021/jm051009k

Source and publish data:

Journal of Medicinal Chemistry p. 2055 - 2062 (2006)

Update date:2022-07-31

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Authors:

Chong, Hyun-Soon

Garmestani, Kayhan

Bryant Jr., L. Henry

Milenic, Diane E.

Overstreet, Terrish

Birch, Noah

Le, Thien

Brady, Erik D.

Brechbiel, Martin W.

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Article abstract of DOI:10.1021/jm051009k

Novel chelates PIP-DTPA, AZEP-DTPA, NETA, NPTA, and PIP-DOTA were synthesized and evaluated as potential magnetic resonance imaging (MRI) contrast enhancement agents. The T₁ and T₂ relaxivities of their corresponding Gd(III) complexe

Full text of DOI:10.1021/jm051009k

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