Acetylenic Nucleosides. 3. Synthesis and Biological Activities of Some 5-Ethynylpyrimidine Nucleosides

DOI: 10.1021/jm00369a032

Source and publish data:

Journal of Medicinal Chemistry p. 410 - 412 (1984)

Update date:2022-07-29

Topics:

Authors:

Sharma, Ram A.

Kavai, Ivan

Hughes, Robert G.

Bobek, Miroslav

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Article abstract of DOI:10.1021/jm00369a032

Iodination of 1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil furnished the 5-iodo derivative (Ib), which on treatment with (trimethylsilyl)acetylene in the presence of catalytic amounts of (Ph3P)2PdCl2/CuI and subsequent deblocking, afforded 1-β-D-arab

Full text of DOI:10.1021/jm00369a032

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