Acetylenic Nucleosides. 3. Synthesis and Biological Activities of Some 5-Ethynylpyrimidine Nucleosides

DOI: 10.1021/jm00369a032

Source and publish data:

Journal of Medicinal Chemistry p. 410 - 412 (1984)

Update date:2022-07-29

Topics:

Authors:

Sharma, Ram A.

Kavai, Ivan

Hughes, Robert G.

Bobek, Miroslav

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00369a032

Iodination of 1-(2,3,5-tri-O-acetyl-β-D-arabinofuranosyl)uracil furnished the 5-iodo derivative (Ib), which on treatment with (trimethylsilyl)acetylene in the presence of catalytic amounts of (Ph3P)2PdCl2/CuI and subsequent deblocking, afforded 1-β-D-arab

Full text of DOI:10.1021/jm00369a032

Products guided by the article

Product name:1-(2-deoxy-2-fluoro-α-D-arabinofuranosyl)-5-ethynylcytosine

Cas No:88425-54-1

R&D Labs maybe for 88425-54-1

Sinochem Jiangsu Co.,Ltd.

Contact:86-25-51817806

Address:No. 216, middle longpan road, jincheng tower, floor 21-22, nanjing ,china
Huayang chemical Co., LTD

Contact:+86-18653358619

Address:zibo
RongCheng K&S Chemical Co.,Ltd

Contact:0631-7336369

Address:rongcheng ,shandong province china
Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue

Relevant to this article

A chiral hypervalent iodine(III) reagent for enantioselective dearomatization of phenols

Doi:10.1002/anie.200800464
(2008)
The [4+2]-Cycloaddition of α-Nitrosoalkenes with Thiochalcones as a Prototype of Periselective Hetero-Diels–Alder Reactions—Experimental and Computational Studies

Doi:10.1002/chem.201903385
(2020)
Biodegradable Chitosan-Derived Thioureas as Recoverable Supported Organocatalysts – Application to the Stereoselective Aza-Henry Reaction

Doi:10.1002/ejoc.201700582
(2017)
Vinylsulfones as nucleophiles and Michael acceptors in the same step: Stereoselective synthesis of amino acid precursors

Doi:10.1055/s-2005-870005
(2005)
Synthesis and characterization of Δlac-acetogenins that potently inhibit mitochondrial complex I

Doi:10.1016/j.bmc.2008.10.071
(2009)
Doi:10.1021/jo01162a009
(1948)

Article Doi