Amino acids and peptides. IX. Synthesis of cysteine-containing peptide fragments related to human hepatic metallothionein II (hMT II) and determination of their heavy metal-binding properties

DOI: 10.1248/cpb.31.3094

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3094 - 3103 (1983)

Update date:2022-08-05

Topics:

Authors:

Ohta Ohta

Okada Okada

Tanaka Tanaka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.31.3094

Eight kinds of cysteine-containing peptides related to human hepatic metallothionein were synthesized by conventional methods. The metal-binding properties of these peptides with Zn²⁺ and Cd²⁺ were indicated by an increase of ultraviolet absorbance resulting from mercaptide formation. The Cd-binding activities of various peptides obtained here were assessed by measuring the increase in absorbance of mercaptide at 250 mm as a function of the concentration of Cd. The binding abilities of the peptides with Cd differed substantially.

Full text of DOI:10.1248/cpb.31.3094

NII-Electronic Library Service

Products guided by the article

Product name:Boc-Lys(Z)-Cys(MBzl)-Lys(Z)-NHNH₂

Cas No:88831-94-1

R&D Labs maybe for 88831-94-1

Rudong Zhenfeng Yiyang Chemical Co., Ltd.

Contact:0513-84573047

Address:South Fengli Town, Rudong County, Jiangsu Province, China
Shanghai Kefu Chemical Co.,Ltd.

Contact:+86-21-34616196

Address:Room601-602, Xuhui Business Building, No.168, Yude Road, Shanghai
Nanjing Habo Medical Technology Co., Ltd.

Contact:025－85769882

Address:No.108. Ganjiabian east. Qixia District .Nanjing
Changde Yungang Biotechnology Co., Ltd

website:http://www.cdyg.com

Contact:+86-736-7391178

Address:Qiaonan Industrial Park, Changde City, Hunan Province
WUHAN RISON TRADING CO.,LTD

Contact:0086-27-83607103/83642615

Address:No.498, Jianshe Ave, Wuhan, China

Relevant to this article

DMF as carbon source: Rh-catalyzed α-methylation of ketones

Doi:10.1021/ol403040g
(2014)
Synthesis of 4-alkyl-3,4-dihydronaphtho[2,3-f]quinoxaline-2,7,12-(1H)- triones and 3-alkyl-5-arylamino-2-chloromethyl-3H-anthra[1,2-d]imidazole-6,11- diones based on reactions of 1-amino-9,10-anthraquinones with chloroacetyl chloride

Doi:10.1007/s11172-010-0316-8
(2010)
A new methodology for the synthesis of fluorinated exo-glycals and their time-dependent inhibition of UDP-galactopyranose mutase

Doi:10.1002/chem.200500991
(2006)
Enantioselective and diastereoselective syntheses of cyanohydrin carbonates

Doi:10.1016/j.tet.2007.07.016
(2007)
Studies on the constituents of Asclepiadaceae plants. LVI. Isolation of new antitumor-active glycosides from Dregea volubilis (L.) BENTH.

Doi:10.1248/cpb.31.3971
(1983)
Asymmetric hetero-Diels-Alder reaction of diazenes catalyzed by chiral silver phosphate: Water participates in the catalysis and stereocontrol

Doi:10.1021/ol503047s
(2014)

Article Doi