Amino acids and peptides. IX. Synthesis of cysteine-containing peptide fragments related to human hepatic metallothionein II (hMT II) and determination of their heavy metal-binding properties

DOI: 10.1248/cpb.31.3094

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3094 - 3103 (1983)

Update date:2022-08-05

Topics:

Authors:

Ohta Ohta

Okada Okada

Tanaka Tanaka

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.31.3094

Eight kinds of cysteine-containing peptides related to human hepatic metallothionein were synthesized by conventional methods. The metal-binding properties of these peptides with Zn²⁺ and Cd²⁺ were indicated by an increase of ultraviolet absorbance resulting from mercaptide formation. The Cd-binding activities of various peptides obtained here were assessed by measuring the increase in absorbance of mercaptide at 250 mm as a function of the concentration of Cd. The binding abilities of the peptides with Cd differed substantially.

Full text of DOI:10.1248/cpb.31.3094

NII-Electronic Library Service

Products guided by the article

Product name:Boc-Lys(Z)-Cys(MBzl)-Lys(Z)-NHNH₂

Cas No:88831-94-1

R&D Labs maybe for 88831-94-1

Ningbo Huajia Chemicals

Contact:+86-574-87065746

Address:10th Floor, No.787 Baizhang East Road,
shanghai Tauto Biotech Co., Ltd

website:http://www.tautobiotech.com/en/index.htm

Contact:+86-21-51320588 ext. 8025

Address:No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA
Changsha Goomoo Chemical Technology Co.Ltd

Contact:+86-731-82197655

Address:No.649,Chezhan Rd.(N),Changsha,Hunan,China
YanCheng LongShen Chemical Co.,Ltd.

Contact:+86-515-86668866

Address:No.13,Weiyi Road,Funing Aoyang Industrial Park
Hebei Kangtai Pharmaceutical Co.,Ltd

Contact:+86-0317-3512963

Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China

Relevant to this article

DMF as carbon source: Rh-catalyzed α-methylation of ketones

Doi:10.1021/ol403040g
(2014)
Synthesis of 4-alkyl-3,4-dihydronaphtho[2,3-f]quinoxaline-2,7,12-(1H)- triones and 3-alkyl-5-arylamino-2-chloromethyl-3H-anthra[1,2-d]imidazole-6,11- diones based on reactions of 1-amino-9,10-anthraquinones with chloroacetyl chloride

Doi:10.1007/s11172-010-0316-8
(2010)
A new methodology for the synthesis of fluorinated exo-glycals and their time-dependent inhibition of UDP-galactopyranose mutase

Doi:10.1002/chem.200500991
(2006)
Enantioselective and diastereoselective syntheses of cyanohydrin carbonates

Doi:10.1016/j.tet.2007.07.016
(2007)
Studies on the constituents of Asclepiadaceae plants. LVI. Isolation of new antitumor-active glycosides from Dregea volubilis (L.) BENTH.

Doi:10.1248/cpb.31.3971
(1983)
Asymmetric hetero-Diels-Alder reaction of diazenes catalyzed by chiral silver phosphate: Water participates in the catalysis and stereocontrol

Doi:10.1021/ol503047s
(2014)

Article Doi