OBTENTION D'AMINO-2 THIAZOLES-1,3 PAR ACTION D'AMINES PRIMAIRES SUR DES α-HALO β-THIOCYANATO ALCENES

Article abstract of DOI:10.1016/S0040-4039(00)94047-4

Action of primary amines on vic-halo-thiocyanato alkenes R¹-C(-SCN)=CX-R%&2 affords 2-amino 1,3-thiazoles, the cyclisation taking place with migration of the sulphur atom on the C=C bond; thus 2-cyclohexylamino 5-propyl 1,3-thiazole is obtained