SYNTHESIS OF A SUBSTITUTED 2,6-DIOXABICYCLOHEPTANE, 1,3-ANHYDRO-2,4,6-TRI-O-BENZYL-β-D-GLUCOPYRANOSE

Article abstract of DOI:10.1016/S0008-6215(00)85898-X

1,3-Anhydro-2,4,6-tri-O-benzyl-β-D-glucopyranose has been synthesized by ring closure of 2,4,6-tri-O-benzyl-α-D-glucopyranosyl chloride via two reaction sequences.The preferable method has allyl 3-O-allyl D-glucopyranoside as key intermediate.This appears to be the first example of an anhydro sugar derivative with the 2,6-dioxabicyclo<3.1.1>heptane skeleton.