Helvetica Chimica Acta p. 368 - 373 (1986)
Update date:2022-08-03
Topics:
Julina, Radomir
Herzig, Thomas
Bernet, Bruno
Vasella, Andrea
The enynol 2 was transformed into D-erythro-sphingosine 11 (7 steps, 46 percent) and into ceramide 1 (8 step, 41 percent overall yield).The key steps were the mono-epoxidation of the enynol 5 (Ti(t-BuO)4, (-)-D-diethyl tartrate, t-BuOOH) to 6 (86percent, >/= 98percent ee), the regioselective intramolecular opening of the oxirane 6 via the benzylurethane 7, and the reductive transformation of the acetylene 9 into the oxazolidinone 10 (Li, EtNH2, 88 percent).
View MoreChongqing Yawei Fine Chemical Co.,Ltd
Contact:0086-23-62849407
Address:Ziyou village, Nanquan town, Banan district, Chongqing China
website:http://www.chinabarton.com
Contact:+86-573-82719618
Address:No. 162 Fumin Road, Honghe Town,
MTT Pharma & Bio-technology Co.,Ltd(expird)
Contact:+86-21-58407925
Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
Contact:+86-633-8332928
Address:No.1,Huanghai Yilu.Rizhao,Shandong
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
Doi:10.1016/j.ejmech.2019.02.048
(2019)Doi:10.1016/j.bmcl.2005.08.098
(2005)Doi:10.1016/S0040-4039(00)87693-5
(1982)Doi:10.1021/ol0491991
(2004)Doi:10.1081/SCC-200061564
(2005)Doi:10.1002/asia.202000154
(2020)
