Total Synthesis of (-)-Neplanocin A

DOI: 10.1021/jo00259a019

Source and publish data:

Journal of Organic Chemistry p. 5709 - 5714 (1988)

Update date:2022-08-05

Topics: Enantioselective Nuclear magnetic resonance (NMR) spectroscopy Total synthesis Nucleophilic substitution Stereoselective High-performance liquid chromatography (HPLC) Protecting group Retrosynthetic analysis Diels-Alder Reaction Chiral Auxiliary Neplanocin A

Authors:

Marquez, Victor E.

Lim, Mu-Ill

Tseng, Christopher K.-H.

Markovac, Anica

Priest, Matthew A.

et al. et al.

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Article abstract of DOI:10.1021/jo00259a019

An efficient synthesis of neplanocin A, which is easily adaptable for the preparation of other cyclopentenyl containing nucleoside isosteres, has been developed.This enantioselective synthesis provides control of two of the three chiral centers of neplano

Full text of DOI:10.1021/jo00259a019

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