ACYLATION OF 1-HYDROXYAMINO-2-HYDROXYIMINOETHANES WITH α-HALO ACID CHLORIDES AND THE PREPARATION OF 1-HYDROXY-2-OXOTETRAHYDROPYRAZINE 4-OXIDES

Article abstract of DOI:10.1007/BF00505860

The acylation of 1-hydroxyamino-2-hydroxyiminoethanes with α-halo acid chlorides has given the products of N- and O-acylation at the hydroxyamino group.The action of bases on the product of N-acylation-N - (2-hydroxyiminoalkyl)-2-halohydroxamic acids - has given, depending on the conditions, 1-hydroxy-2-oxo-1,2,3,6- or -1,2,5,6-tetrahydropyrazine 4-oxides and 1,2-oxazetidin-3-ones.