ASYMMETRIC ACYLATION OF CARBOXAMIDES HAVING trans-2,5-BIS(METHOXYMETHOXYMETHYL)PYRROLIDINE MOIETY AS A CHIRAL AUXILIARY AND STEREOSELECTIVE REDUCTION OF THE RESULTING 2-ALKYL-3-OXO AMIDES

DOI: 10.1016/S0040-4039(01)81747-0

Source and publish data:

Tetrahedron Letters p. 6015 - 6016 (1984)

Update date:2022-07-30

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Authors:

Ito, Yoshio

Katsuki, Tsutomu

Yamaguchi, Masaru

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Article abstract of DOI:10.1016/S0040-4039(01)81747-0

trans-2,5-Bis(methoxymethoxymethyl)pyrrolidine proved to be an excellent chiral auxiliary for the asymmetric acylation of the corresponding carboxamide enolates and the stereoselective Zn(BH4)2 reduction of the resulting 2-alkyl-3-oxo amides provided a us

Full text of DOI:10.1016/S0040-4039(01)81747-0

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