Chemistry Letters p. 441 - 444 (1984)
Update date:2022-08-02
Topics:
Ohfune, Yasufumi
Kurokawa, Natsuko
Higuchi, Naoki
Saito, Masayuki
Hashimoto, Masaki
et al.
Reactions of protection-free α-amino acids with aldehydes or ketones in the presence of sodium cyanoborohydride afforded the N-monoalkylated amino acids in inorganic salt-free form.Application of this method to synthesis of N-alkyl derivatives of biologic
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