AN EFFICIENT ONE-STEP REDUCTIVE N-MONOALKYLATION OF α-AMINO ACIDS

DOI: 10.1246/cl.1984.441

Source and publish data:

Chemistry Letters p. 441 - 444 (1984)

Update date:2022-08-02

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Authors:

Ohfune, Yasufumi

Kurokawa, Natsuko

Higuchi, Naoki

Saito, Masayuki

Hashimoto, Masaki

et al. et al.

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Article abstract of DOI:10.1246/cl.1984.441

Reactions of protection-free α-amino acids with aldehydes or ketones in the presence of sodium cyanoborohydride afforded the N-monoalkylated amino acids in inorganic salt-free form.Application of this method to synthesis of N-alkyl derivatives of biologic

Full text of DOI:10.1246/cl.1984.441

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