Organic Letters p. 3227 - 3230 (2006)
Update date:2022-08-05
Topics:
Detz, Remko J.
Heras, Silvia Arevalo
De Gelder
Van Leeuwen, Piet W. N. M.
Hiemstra, Henk
Reek, Joost N. H.
Van Maarseveen, Jan H.
A novel P,N-type ligand family (ClickPhine) is disclosed that is easily accessible using the Cu(I)-catalyzed azide-alkyne "click" cycloaddition. A diverse set of ligands was made in just three steps from readily available starting materials to give several homogeneous and a heterogeneous catalyst. Preliminary experiments show the efficacy of these ligands in the Pd-catalyzed allylic alkylation reaction.
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Doi:10.1016/j.jorganchem.2006.04.038
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(2006)