Journal of Medicinal Chemistry p. 311 - 317 (1985)
Update date:2022-09-26
Topics:
Gessner, Wieslaw
Brossi, Arnold
Shen, Rong-sen
Abell, Creed W.
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a nigrostriatal neurotoxin which can cause irreversible parkinsonism in humans and primates by selective destruction of neurons in the substantia nigra.It is possible that MPTP could be metabolized by
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