Regioselective synthesis of (+)-S-2-amino-5-iodoacetamidopentanoic and (+)-S-2-amino-6-iodoacetamidohexanoic acids

Article abstract of DOI:10.1080/00397919108020837

Mild reaction conditions were developed for the preparation of the active-site-directed irreversible enzyme inhibitors (+)-S-2-amino-5-iodoacetamido-pentanoic acid and (+)-S-2-amino-6-iodoacetamido-hexanoic acid.

Full text of DOI:10.1080/00397919108020837

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Synthetic Communications: An
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Regioselective Synthesis
of (+) -S-2-Amino-5-
iodoacetamidopentanoic
and (+) -S-2-amino-6-
iodoacetamidohexanoic Acids
J. G. Trujillo a , G. Ceballos a , R. Yañez a & P.
Joseph-Nathan b
a Sección de Graduados y Departmento de
Bioquímica y Biofísica , Escuela Superior de Medicina
del Instituto Politécnico Nacional , Apartado 42 -
161, México, D.F., México(Becarios COFAA)
b Departamento de Química del Centro de
Investigación y de Estudios Avanzados , Instituto
Politécnico Nacional , Apartado 14-740, México, D.
F., 07000, México
Published online: 23 Sep 2006.
To cite this article: J. G. Trujillo , G. Ceballos , R. Yañez & P. Joseph-Nathan (1991)
Regioselective Synthesis of (+) -S-2-Amino-5-iodoacetamidopentanoic and (+) -S-2-
amino-6-iodoacetamidohexanoic Acids, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 21:5, 683-691, DOI:
10.1080/00397919108020837
To link to this article: http://dx.doi.org/10.1080/00397919108020837

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