Synthesis and Evaluation of Substituted 2-Phenylcyclobutylamines as Analogues of Hallucinogenic Phenethylamines: Lack of LSD-like Biological Activity

DOI: 10.1021/jm00375a004

Source and publish data:

Journal of Medicinal Chemistry p. 1108 - 1111 (1984)

Update date:2022-08-04

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Authors:

Nichols, David E.

Jadhav, Kiran P.

Oberlender, Robert A.

Zabik, Joseph E.

Bossart, Josef F.

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Article abstract of DOI:10.1021/jm00375a004

cis- and trans-2-(2,4,5-trimethoxyphenyl)cyclobutylamine and trans-2-(2,5-dimethoxy-4-methylphenyl)cyclobutylamine were synthesized as conformationally restricted analogues of hallucinogenic phenylisopropylamines.In rats trained to discriminate saline fro

Full text of DOI:10.1021/jm00375a004

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