Journal of Pharmaceutical Sciences p. 352 - 354 (1985)
Update date:2022-08-03
Topics:
Wu
Douglas
Ondeyka
Payne
Ikeler
Joshua
Patchett
The synthesis and some of the spectral properties of N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline (lisinopril, MK-521) are described. This compound inhibits angiotensin-converting enzyme with an IC50 of 1.2 X 10(-9) M.
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