2,5-disubstituted pyrrolidines: Versatile regioselective and diastereoselective synthesis by enamine reduction and subsequent alkylation

DOI: 10.1039/b303789d

Source and publish data:

Organic and Biomolecular Chemistry p. 1838 - 1841 (2003)

Update date:2022-08-04

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Authors:

Hussaini, Syed Raziullah

Moloney, Mark G.

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Article abstract of DOI:10.1039/b303789d

A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of enamines derived from pyroglutamic acid is reported.

Full text of DOI:10.1039/b303789d

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