Scientia Pharmaceutica p. 101 - 112 (2005)
Update date:2022-08-04
Topics:
Jasztold-Howorko, Ryszard
Doroszkiewicz, W?odzimierz
Bugla-P?oskon?ska, Gabriela
Croisy, Alain
Carrez, Daniele
Starting from 2-(6-methoxy-1-methyl-9H-carbazol-2-yl)ethylamine and 2-methylisonicotinic acid, 9-hydroxy-5,6-dimethyl-1-(2-methylpyridin-4-yl)-6H- pyrido[4,3-b]carbazole (5) was obtained. The new compound showed significant cytostatic activity for cultured L1210 cells and no inhibition of growth of the E. coli O56 strain was observed. The bactericidal activity of normal human serum against E. coli O56 was not affected by the examined compound 5 and its isomer 4. O?sterreichische Apotheker-Verlagsgesellschaft m. b. H.
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