Design and synthesis of an orally active matrix metalloproteinase inhibitor

DOI: 10.1016/j.bmc.2006.05.040

Source and publish data:

Bioorganic and Medicinal Chemistry p. 6383 - 6403 (2006)

Update date:2022-08-03

Topics:

Authors:

Yamamoto, Shingo

Nakatani, Shingo

Ikura, Masahiro

Sugiura, Tsuneyuki

Nishita, Yoshitaka

Itadani, Satoshi

Ogawa, Koji

Ohno, Hiroyuki

Takahashi, Kanji

Nakai, Hisao

Toda, Masaaki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.bmc.2006.05.040

A series of 4-(4-phenoxy)benzoylamino-4-methoxymethyloxymethyl butyric acid hydroxamates, which were derived from l-glutamic acid, were synthesized and evaluated as matrix metalloproteinase inhibitors. Most of the compounds listed in Tables 1-3 exhibited

Full text of DOI:10.1016/j.bmc.2006.05.040

Products guided by the article

Product name:benzyl (4S)-4-(tert-butoxycarbonyl)amino-5-[(2,2-dimethylpropanoyl)oxy]pentanoate

Cas No:911050-94-7

R&D Labs maybe for 911050-94-7

XI'AN CHUKANG BIOTECHNOLOGY CO.,LTD

Contact:29-63685658 63685359

Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Xi'an North Information Industry Co., Ltd. Weilv Chemical Department

Contact:+86-29-88156413

Address:Jixiang Road 99 Xi'an Shaanxi Province
TAIZHOU XINGCHENG CHEMPHARM CO.,LTD.

Contact:0086-0576-88551200,88886292 ,88880039

Address:B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Tianjin Anda North Industrial & Business Co.Ltd.

Contact:86-22-24999306

Address:No.11 Erwei Road,Dongli Development Area,Tianjin,China

Relevant to this article

Efficient synthesis of chiral phenethylamines: preparation, asymmetric hydrogenation, and mild deprotection of ene-trifluoroacetamides

Doi:10.1016/j.tetlet.2006.06.135
(2006)
First synthesis and determination of the absolute stereochemistry of iso-cladospolide-B and cladospolides-B and C

Doi:10.1016/j.tetlet.2006.07.044
(2006)
Unusual synthesis of new glycine antagonists via sequential aldol condensation-lactonization-elimination reaction

Doi:10.1016/S0960-894X(98)00284-4
(1998)
Synthesis and charaterization of 1,3,4-oxadiazoles carrying triazolopyridinone and carbazole as the potential bluish-green electroluminescent materials for the single layer device

Doi:10.3987/COM-06-10758
(2006)
Dichloro<1,2-bis(4-hydroxyphenyl)ethylenediamine>platinium(II) Complexes: An Approach To Develop Compounds with a Specific Effect on the Hormone-Dependent Mammary Carcinoma

Doi:10.1021/jm00376a009
(1984)
Determination of Enantiomeric Purities of Alcohols and Amines by a 31P NMR Technique

Doi:10.1021/ja00329a072
(1984)

Article Doi