Tetrahedron Letters p. 1545 - 1548 (2007)
Update date:2022-08-04
Topics:
Shimbashi, Akiko
Nishiyama, Shigeru
Chloroquinocin 1 is an antimicrobial agent against Gram-positive bacteria, including MRSA (methicillin-resistant Staphylococcus aureus). A successful synthesis of 1 was attained through a unique chlorination of the corresponding naphthoquinone derivative 12 as a key step.
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