Synthesis and?antitumour activity of?new muricatacin and?goniofufurone analogues

Article abstract of DOI:10.1016/j.ejmech.2006.06.008

A divergent approach to the 7-oxa (-)-muricatacin analogue 2, the corresponding (+)-enantiomer ent-2 and the furanolactone 3 is reported starting from d-xylose. The resulting lactones have shown a potent and selective in vitro cytotoxicity against certain