Studies on the Syntheses of Heterocyclic Compounds. Part 877. An Alternative Synthesis of Protected (+/-)-Thienamycin and a Related Compound

DOI: 10.1039/P19810000964

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 964 - 968 (1981)

Update date:2022-08-04

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Authors:

Kametani, Tetsuji

Huang, Shyh-Pyng

Nagahara, Takayasu

Yokohama, Shuichi

Ihara, Masataka

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Article abstract of DOI:10.1039/P19810000964

An alternative total synthesis of protected (+/-)-thienamycin (2) and an analogue is described. (+/-)-4β-(2,2-Dimethoxyethyl)-3α-<(1R^*)-1-(-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one (5), prepared from isoxazoline derivatives (4), was conve

Full text of DOI:10.1039/P19810000964

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Product name:(+/-)-4β-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one

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