Novel syntheses of chiral β- and γ-amino acid derivatives utilizing N-protected (aminoacyl)benzotriazoles from aspartic and glutamic acids

Article abstract of DOI:10.1021/jo061667s

Friedel-Crafts reactions of N-protected (α-aminoacyl)benzotriazoles with hetero- and benzenoid- aromatics give α-amino ketones that can be reduced by either triethyl silane or sodium borohydride to form the corresponding β- and γ-amino acid derivatives. T